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The peptide's safety profile has been established through extensive animal studies and human clinical trials, with minimal side effects reported even during long-term administration protocols extending multiple years

However, there are some problems that must be noted

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Notably, mice that developed vascular lesions in the context of EAE exhibited heightened VEGF expression, indicative of its pivotal role in the pathogenesis of neuroinflammatory disorders (Roscoe and Welsh 2009)

Leonardi C, See K, Gallo G, McKean-Matthews M, Zhang Y, Goldblum O, Mallbris L, Burge R (2021) Psoriasis severity assessment combining physician and patient reported outcomes: the optimal psoriasis assessment tool

Additionally, specific orders such as brassicales (73), poales (81), asterids (95) and eukaryota (15)